Silzin (Silver Sulphadiazine 1% cream) is a local chemotherapeutic agent, used topically for the prevention & treatment of infection of wounds from burns. It has a broad antibacterial spectrum including virtually all microbial species likely to infect burn wounds. It is also an effective agent against Candida albicans and other fungi. It has a bactericidal action in contrast to Sulphadiazine.

Silzin cream penetrates into the necrotic tissue and exudate. This effect is very important in view of the
fact that systemic antibiotics are not effective against the bacterial flora of vascular burn necrosis.  The compound is painless upon application. It also has a pleasant cooling effect to the burnt surface.

Silzin cream is indicated in -

• Prophylaxis and treatment of infection in burn wounds
• As an adjunct to short-term treatment of infection in Leg ulcers & Pressure sores
• As an adjunct to prophylaxis of infection in Skin graft donor sites & Extensive abrasions
• Conservative management of finger-tip injuries