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Atopen-X Tablet
Generic Name : Paracetamol BP + Tramadol HCl BP
Therapeutic Class : Multi-modal Analgesic Combination
Dosage form : Tablet
Pack Size : 2x10's.

Tramadol  is  a  centrally  acting  synthetic  opioid.  It  is  a  pure  non-selective  agonist  of  the μ, Δ and κ    opioid receptors with higher affinity for the µ receptors. Unlike morphine, a broad range of analgesic doses of Tramadol has no respiratory depression effect.    Tramadol  has  been  shown  to  inhibit  re-uptake  of  norepinephrine  &  serotonin  in  vitro,  as  have  some other opioids analgesics. These mechanisms may contribute independent  to the overall analgesic profile of tramadol. Paracetamol is non-opiate and non-salicylate analgesic with marked anti-pyretic property. The precise mechanism of the analgesic properties of paracetamol is unknown and may involve central and pheripheral mechanisms.

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