Inflect tablet consists of an immediate release Esomeprazole magnesium layer and an enteric coated Naproxen core. The  enteric  coating  prevents  the  release  of  Naproxen  at  p^H  levels below 5.5. As a result Esomeprazole is released first into the stomach, prior to the dissolution of Naproxen in the small intestine. Naproxen is a NSAID with analgesic and antipyretic properties. The mechanism of action of the Naproxen anion, like other NSAIDs, is not completely understood but may be related to prostaglandin synthetase inhibition. Esomeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H⁺/K⁺-ATPase in the gastric parietal cells. By  acting  specifically  on  the  proton  pump, Esomeprazole  blocks the final step in acid production, thus reducing gastric acidity.